Modification of Outcomes With Aspirin or Apixaban in Relation to CHADS 2 and CHA 2 DS 2 -VASc Scores in Patients With Atrial Fibrillation

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CHADS(2) and CHA(2)DS(2)VASc scores as predictors of cardioembolic sources in secondary stroke prevention.

INTRODUCTION AND OBJECTIVES Cardioembolism is one of the most common causes of ischemic stroke, with an estimated prevalence of 20-30%, and correct diagnosis is essential given the therapeutic implications. Although stroke risk scores (CHADS2 and more recently CHA2DS2-VASc) have been validated in heterogeneous populations of patients with atrial fibrillation, their accuracy has not been ascerta...

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Long‐Term Stroke Risk Prediction in Patients With Atrial Fibrillation: Comparison of the ABC‐Stroke and CHA 2 DS 2‐VASc Scores

BACKGROUND The ABC-stroke score (age, biomarkers [N-terminal fragment B-type natriuretic peptide, high-sensitivity troponin], and clinical history [prior stroke/transient ischemic attack]) was proposed to predict stroke in atrial fibrillation (AF). This score was derived/validated in 2 clinical trial cohorts in which patients with AF were highly selected and carefully followed-up. However, the ...

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Use of the CHA(2)DS(2)-VASc and HAS-BLED scores to aid decision making for thromboprophylaxis in nonvalvular atrial fibrillation.

A 65-year-old woman with a history of myocardial infarction presented to the emergency department with palpitations. ECG on admission documented atrial fibrillation (AF), which subsequently reverted spontaneously to sinus rhythm. Echocardiogram revealed mild systolic impairment, normal left atrial size, and normal valves. Thyroid function tests were normal. She returned to the outpatient clinic...

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Modification of outcomes with aspirin or apixaban in relation to female and male sex in patients with atrial fibrillation: a secondary analysis of the AVERROES study.

BACKGROUND AND PURPOSE The main objective of the present analysis was to assess the effect of treatment with aspirin compared with apixaban on ischemic stroke and major bleeding in women compared with men. Female patients with atrial fibrillation are at increased stroke risk compared with male patients, and the underlying reasons for higher risk are uncertain. METHODS Ancillary analysis of th...

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Acetylsalicylic Acid to Prevent Stroke in Atrial Fibrillation Patients Who Have Failed or Are Unsuitable for Vitamin K Antagonist Treatment (AVERROES) study was conducted to estimate event rates in different low-risk cohorts by treatment. Three cohorts (n=1000) with a CHADS

Atrial fibrillation (AF) is associated with a 4to 5-fold increase in the risk of experiencing stroke. Because of the mortality and morbidity associated with ischemic stroke, AF imposes a 1.5-fold increase in the cost of care, and the risk of death from AF-related stroke is doubled. Anticoagulation treatment is recommended to mitigate the risk of stroke in patients with AF, which for the past 5 ...

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ژورنال

عنوان ژورنال: Circulation: Arrhythmia and Electrophysiology

سال: 2013

ISSN: 1941-3149,1941-3084

DOI: 10.1161/circep.112.975847